Thirty years after scientists coined the term “hygiene hypothesis” to suggest that increased exposure to microorganisms could benefit health, University of Colorado Boulder researchers have identified an anti-inflammatory fat in a soil-dwelling bacterium that may be responsible.
The discovery, published Monday in the journal Psychopharmacology, may at least partly explain how the bacterium, Mycobacterium vaccae, quells stress-related disorders. It also brings the researchers one step closer to developing a microbe-based “stress vaccine.”
“We think there is a special sauce driving the protective effects in this bacterium, and this fat is one of the main ingredients in that special sauce,” said senior author and Integrative Physiology Professor Christopher Lowry.
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